If a publication contains digital enhancements that are important enough to warrant preservation, the publication inclusive of its enhancements may be substantial enough to warrant a new ISBN, DOI, or other persistent identifier. This practice would ensure that the new version can be easily distinguished from other unenhanced versions of the publication in the preservation system.
These guidelines also relate to management of versions and use of identifiers:
9. Define the “version of record” in your context
17. Use persistent identifiers to link or cite external resources
23. Include version information in bibliographic metadata